Correlation of Vaccine-Elicited Systemic and Mucosal Nonneutralizing Antibody Activities with Reduced Acute Viremia following Intrarectal Simian Immunodeficiency Virus SIV(mac251) Challenge of Rhesus Macaques

Cell-mediated immunity and neutralizing antibodies contribute to control of human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) infection, but the role of nonneutralizing antibodies is not defined. Previously, we reported that sequential oral/oral or intranasal/oral (I/O) priming wi...

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Autores principales: Hidajat, Rachmat, Xiao, Peng, Zhou, Qifeng, Venzon, David, Summers, L. Ebonita, Kalyanaraman, Vaniambadi S., Montefiori, David C., Robert-Guroff, Marjorie
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612365/
https://ncbi.nlm.nih.gov/pubmed/18971271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01672-08
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