Sequential Priming with Simian Immunodeficiency Virus (SIV) DNA Vaccines, with or without Encoded Cytokines, and a Replicating Adenovirus-SIV Recombinant Followed by Protein Boosting Does Not Control a Pathogenic SIV(mac251) Mucosal Challenge

Previously, combination DNA/nonreplicating adenovirus (Ad)- or poxvirus-vectored vaccines have strongly protected against SHIV(89.6P), DNAs expressing cytokines have modulated immunity elicited by DNA vaccines, and replication-competent Ad-recombinant priming and protein boosting has strongly protec...

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Detalhes bibliográficos
Main Authors: Demberg, Thorsten, Boyer, Jean D., Malkevich, Nina, Patterson, L. Jean, Venzon, David, Summers, Ebonita L., Kalisz, Irene, Kalyanaraman, V. S., Lee, Eun Mi, Weiner, David B., Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573219/
https://ncbi.nlm.nih.gov/pubmed/18753198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01129-08
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