Antiretroviral Therapy Partly Reverses the Systemic and Mucosal Distribution of NK Cell Subsets that is Altered by SIV(mac251) Infection of Macaques

We characterized three subsets of NK cells in blood, and two subsets in mucosal tissues. SIV(mac251) infection increased total and CD16(+) NK cells in the blood. In the rectum, we observed a significant increase in total and NKG2A(+) NK cells during SIV infection. In contrast, the NKp44(+) subset si...

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Gepubliceerd in:Virology
Hoofdauteurs: Liyanage, Namal P. M., Gordon, Shari N., Doster, Melvin N., Pegu, Poonam, Vaccari, Monica, Shukur, Nebiyu, Schifanella, Luca, Pise-Masison, Cynthia A., Lipinska, Danuta, Grubczak, Kamil, Moniuszko, Marcin, Franchini, Genoveffa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008240/
https://ncbi.nlm.nih.gov/pubmed/24503100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.12.003
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