Antibody to the gp120 V1/V2 loops and CD4(+)and CD8(+) T-cell responses in protection from SIV(mac251) vaginal acquisition and persistent viremia

The human papilloma virus pseudovirions (HPV-PsVs) approach is an effective gene-delivery system that can prime or boost an immune response in the vaginal tract of non human primates and mice. Intra-vaginal vaccination with HPV-PsVs expressing SIV genes, combined with an intra-muscular gp120 protein...

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Pubblicato in:J Immunol
Autori principali: Gordon, Shari N., Doster, Melvin N, Kines, Rhonda C., Keele, Brandon F, Cofano, Egidio Brocca, Guan, Yongjun, Pegu, Poonam, Liyanage, Namal P.M., Vaccari, Monica, Cuburu, Nicolas, Buck, Christopher B., Ferrari, Guido, Montefiori, David, Piatak, Mike, Lifson, Jeffrey D, Xenophontos, Anastasia M., Venzon, David, Robert-Guroff, Marjorie, Graham, Barney S., Lowy, Douglas R., Schiller, John T., Franchini, Genoveffa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335709/
https://ncbi.nlm.nih.gov/pubmed/25398324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401504
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