טוען...
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
The precise molecular mechanism of action and targets through which thalidomide and related immunomodulatory drugs (IMiDs) exert their antitumor effects remains unclear. We investigated the role of cereblon (CRBN), a primary teratogenic target of thalidomide, in the antimyeloma activity of IMiDs. CR...
שמור ב:
| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208291/ https://ncbi.nlm.nih.gov/pubmed/21860026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-356063 |
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