Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways

MAP kinase phosphatase 4 (DUSP9/MKP-4) plays an essential role during placental development and is one of a subfamily of three closely related cytoplasmic dual-specificity MAPK phosphatases, which includes the ERK-specific enzymes DUSP6/MKP-3 and DUSP7/MKP-X. However, unlike DUSP6/MKP-3, DUSP9/MKP-4...

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Main Authors: Dickinson, Robin J., Delavaine, Laurent, Cejudo-Marín, Rocío, Stewart, Graeme, Staples, Christopher J., Didmon, Mark P., Trinidad, Antonio Garcia, Alonso, Andrés, Pulido, Rafael, Keyse, Stephen M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207433/
https://ncbi.nlm.nih.gov/pubmed/21908610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255844
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