MCPH1 regulates chromosome condensation and shaping as a composite modulator of condensin II

Mutations in human MCPH1 (hMCPH1) cause primary microcephaly, which is characterized by a marked reduction of brain size. Interestingly, hMCPH1 mutant patient cells display unique cellular phenotypes, including premature chromosome condensation (PCC), in G2 phase. To test whether hMCPH1 might direct...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Yamashita, Daisuke, Shintomi, Keishi, Ono, Takao, Gavvovidis, Ioannis, Schindler, Detlev, Neitzel, Heidemarie, Trimborn, Marc, Hirano, Tatsuya
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207293/
https://ncbi.nlm.nih.gov/pubmed/21911480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106141
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars