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Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

Abnormalities of the hypothalamic-pituitary-adrenal (HPA) axis have been reported in subjects with Alzheimer’s disease (AD) and may include increased cerebrospinal fluid (CSF) cortisol concentrations. Moreover, presence of the APOE ε4 allele, which is an established risk factor for the development o...

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Détails bibliographiques
Auteurs principaux: Bruno, Davide, Nierenberg, Jay J., Ritchie, James C., Lutz, Michael W., Pomara, Nunzio
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207029/
https://ncbi.nlm.nih.gov/pubmed/21803501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2011.07.006
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