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Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

Abnormalities of the hypothalamic-pituitary-adrenal (HPA) axis have been reported in subjects with Alzheimer’s disease (AD) and may include increased cerebrospinal fluid (CSF) cortisol concentrations. Moreover, presence of the APOE ε4 allele, which is an established risk factor for the development o...

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Detalhes bibliográficos
Main Authors: Bruno, Davide, Nierenberg, Jay J., Ritchie, James C., Lutz, Michael W., Pomara, Nunzio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207029/
https://ncbi.nlm.nih.gov/pubmed/21803501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2011.07.006
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