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TOMM40 poly-T variants and Cerebrospinal Fluid Amyloid Beta levels in the elderly

A variable poly-T polymorphism in the TOMM40 gene, which is in linkage disequilibrium with APOE, was recently implicated with increased risk and earlier onset age for late-onset Alzheimer’s disease in APOE ε3 carriers. To elucidate potential neurobiological mechanisms underlying this association, we...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Pomara, Nunzio, Bruno, Davide, Nierenberg, Jay J., Sidtis, John J., Martiniuk, Frank T., Mehta, Pankaj D., Zetterberg, Henrik, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550701/
https://ncbi.nlm.nih.gov/pubmed/21455713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-011-0459-5
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