Lower CSF Amyloid Beta Peptides and Higher F2-Isoprostanes in Cognitively Intact Elderly Individuals With Major Depressive Disorder

OBJECTIVE: Major depressive disorder is common in the elderly, and symptoms are often not responsive to conventional antidepressant treatment, especially in the long term. Soluble oligomeric and aggregated forms of amyloid beta peptides, especially amyloid beta 42, impair neuronal and synaptic funct...

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Detalhes bibliográficos
Main Authors: Pomara, Nunzio, Bruno, Davide, Sarreal, Antero S., Hernando, Raymundo T., Nierenberg, Jay, Petkova, Eva, Sidtis, John J., Wisniewski, Thomas M., Mehta, Pankaj D., Pratico, Domenico, Zetterberg, Henrik, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586557/
https://ncbi.nlm.nih.gov/pubmed/22764362
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