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Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants

Neurofilament light (NFL) proteins in cerebrospinal fluid (CSF) are a marker of neuronal damage, especially subcortical axonal injury and white matter disease. Subjects with Alzheimer’s disease (AD) have shown elevated levels of CSF NFL as compared to controls. However, the presence of the APOE ε4 a...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Bruno, Davide, Pomara, Nunzio, Nierenberg, Jay J., Ritchie, James C., Lutz, Michael W., Zetterberg, Henrik, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550703/
https://ncbi.nlm.nih.gov/pubmed/21983493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2011.09.008
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