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Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

Abnormalities of the hypothalamic-pituitary-adrenal (HPA) axis have been reported in subjects with Alzheimer’s disease (AD) and may include increased cerebrospinal fluid (CSF) cortisol concentrations. Moreover, presence of the APOE ε4 allele, which is an established risk factor for the development o...

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Bibliographic Details
Main Authors: Bruno, Davide, Nierenberg, Jay J., Ritchie, James C., Lutz, Michael W., Pomara, Nunzio
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207029/
https://ncbi.nlm.nih.gov/pubmed/21803501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2011.07.006
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