Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

A series of six novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes was synthesized and characterized in detail by elemental analysis, FT-IR, ESI-MS, HPLC, multinuclear ((1)H, (13)C, (15)N, (195)Pt) NMR spectroscopy and in one case by X-ray diffraction. Cytotoxic properties of the...

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Autors principals: Varbanov, Hristo, Valiahdi, Seied M., Legin, Anton A., Jakupec, Michael A., Roller, Alexander, Galanski, Mathea S., Keppler, Bernhard K.
Format: Artigo
Idioma:Inglês
Publicat: Editions Scientifiques Elsevier 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206992/
https://ncbi.nlm.nih.gov/pubmed/21940073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.09.006
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