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Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

The hormone leptin modulates a diverse range of biological functions, including energy homeostasis and reproduction. Leptin promotes GnRH function via an indirect action on forebrain neurons. We tested whether leptin deficiency or leptin resistance due to a high-fat diet (HFD) can regulate the poten...

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Autors principals: Quennell, Janette H., Howell, Christopher S., Roa, Juan, Augustine, Rachael A., Grattan, David R., Anderson, Greg M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206710/
https://ncbi.nlm.nih.gov/pubmed/21325051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1100
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