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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Obesity in humans and in rodents is usually associated with high circulating leptin levels and leptin resistance. To examine the molecular basis for leptin resistance, we determined the ability of leptin to induce hypothalamic STAT3 (signal transducer and activator of transcription) signaling in C57...

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Bibliografiset tiedot
Päätekijät: El-Haschimi, Karim, Pierroz, Dominique D., Hileman, Stanley M., Bjørbæk, Christian, Flier, Jeffrey S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC378516/
https://ncbi.nlm.nih.gov/pubmed/10862798
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