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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Obesity in humans and in rodents is usually associated with high circulating leptin levels and leptin resistance. To examine the molecular basis for leptin resistance, we determined the ability of leptin to induce hypothalamic STAT3 (signal transducer and activator of transcription) signaling in C57...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: El-Haschimi, Karim, Pierroz, Dominique D., Hileman, Stanley M., Bjørbæk, Christian, Flier, Jeffrey S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC378516/
https://ncbi.nlm.nih.gov/pubmed/10862798
Tagiau: Ychwanegu Tag
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