Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

The hormone leptin modulates a diverse range of biological functions, including energy homeostasis and reproduction. Leptin promotes GnRH function via an indirect action on forebrain neurons. We tested whether leptin deficiency or leptin resistance due to a high-fat diet (HFD) can regulate the poten...

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Hlavní autoři: Quennell, Janette H., Howell, Christopher S., Roa, Juan, Augustine, Rachael A., Grattan, David R., Anderson, Greg M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Neuroendocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206710/
https://ncbi.nlm.nih.gov/pubmed/21325051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1100
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