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Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

The hormone leptin modulates a diverse range of biological functions, including energy homeostasis and reproduction. Leptin promotes GnRH function via an indirect action on forebrain neurons. We tested whether leptin deficiency or leptin resistance due to a high-fat diet (HFD) can regulate the poten...

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Bibliografske podrobnosti
Main Authors: Quennell, Janette H., Howell, Christopher S., Roa, Juan, Augustine, Rachael A., Grattan, David R., Anderson, Greg M.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206710/
https://ncbi.nlm.nih.gov/pubmed/21325051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1100
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