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Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

The hormone leptin modulates a diverse range of biological functions, including energy homeostasis and reproduction. Leptin promotes GnRH function via an indirect action on forebrain neurons. We tested whether leptin deficiency or leptin resistance due to a high-fat diet (HFD) can regulate the poten...

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Bibliografische gegevens
Hoofdauteurs: Quennell, Janette H., Howell, Christopher S., Roa, Juan, Augustine, Rachael A., Grattan, David R., Anderson, Greg M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206710/
https://ncbi.nlm.nih.gov/pubmed/21325051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1100
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