Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

Ataxia telangiectasia–mutated (ATM) and ataxia telangiectasia–related (ATR) kinases are conserved regulators of cellular responses to double strand breaks (DSBs). During meiosis, however, the functions of these kinases in DSB repair and the deoxyribonucleic acid (DNA) damage checkpoint are unclear....

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Hlavní autoři: Joyce, Eric F., Pedersen, Michael, Tiong, Stanley, White-Brown, Sanese K., Paul, Anshu, Campbell, Shelagh D., McKim, Kim S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206348/
https://ncbi.nlm.nih.gov/pubmed/22024169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104121
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