Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

Ataxia telangiectasia–mutated (ATM) and ataxia telangiectasia–related (ATR) kinases are conserved regulators of cellular responses to double strand breaks (DSBs). During meiosis, however, the functions of these kinases in DSB repair and the deoxyribonucleic acid (DNA) damage checkpoint are unclear....

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Autors principals: Joyce, Eric F., Pedersen, Michael, Tiong, Stanley, White-Brown, Sanese K., Paul, Anshu, Campbell, Shelagh D., McKim, Kim S.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206348/
https://ncbi.nlm.nih.gov/pubmed/22024169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104121
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