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Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation

Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication that potentially regulates timing and locations of replication origin firing. Here, we show that viability of fission yeast hsk1Δ cells can be restored by loss of mrc1, which is required for maintenance of replication fork in...

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Hlavní autoři: Matsumoto, Seiji, Hayano, Motoshi, Kanoh, Yutaka, Masai, Hisao
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206344/
https://ncbi.nlm.nih.gov/pubmed/22024164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107025
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