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Rif1 is a global regulator of timing of replication origin firing in fission yeast

One of the long-standing questions in eukaryotic DNA replication is the mechanisms that determine where and when a particular segment of the genome is replicated. Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication and may affect the site selection and timing of origin firing....

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Main Authors: Hayano, Motoshi, Kanoh, Yutaka, Matsumoto, Seiji, Renard-Guillet, Claire, Shirahige, Katsuhiko, Masai, Hisao
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273838/
https://ncbi.nlm.nih.gov/pubmed/22279046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.178491.111
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