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Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation
Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication that potentially regulates timing and locations of replication origin firing. Here, we show that viability of fission yeast hsk1Δ cells can be restored by loss of mrc1, which is required for maintenance of replication fork in...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206344/ https://ncbi.nlm.nih.gov/pubmed/22024164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107025 |
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