Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation

Cdc7/Hsk1 is a conserved kinase required for initiation of DNA replication that potentially regulates timing and locations of replication origin firing. Here, we show that viability of fission yeast hsk1Δ cells can be restored by loss of mrc1, which is required for maintenance of replication fork in...

Full description

Saved in:
Bibliographic Details
Main Authors: Matsumoto, Seiji, Hayano, Motoshi, Kanoh, Yutaka, Masai, Hisao
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206344/
https://ncbi.nlm.nih.gov/pubmed/22024164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107025
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items