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Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast
In fission yeast, replication fork arrest activates the replication checkpoint effector kinase Cds1(Chk2/Rad53) through the Rad3(ATR/Mec1)-Mrc1(Claspin) pathway. Hsk1, the Cdc7 homolog of fission yeast required for efficient initiation of DNA replication, is also required for Cds1 activation. Hsk1 k...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166479/ https://ncbi.nlm.nih.gov/pubmed/21099360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.23.13937 |
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