Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation

Regulated spindle orientation maintains epithelial tissue integrity and stem cell asymmetric cell division. In Drosophila melanogaster neural stem cells (neuroblasts), the scaffolding protein Canoe (Afadin/Af-6 in mammals) regulates spindle orientation, but its protein interaction partners and mecha...

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Autores principales: Wee, Brett, Johnston, Christopher A., Prehoda, Kenneth E., Doe, Chris Q.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206335/
https://ncbi.nlm.nih.gov/pubmed/22024168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102130
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