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Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation
Regulated spindle orientation maintains epithelial tissue integrity and stem cell asymmetric cell division. In Drosophila melanogaster neural stem cells (neuroblasts), the scaffolding protein Canoe (Afadin/Af-6 in mammals) regulates spindle orientation, but its protein interaction partners and mecha...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206335/ https://ncbi.nlm.nih.gov/pubmed/22024168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102130 |
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