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Building cortical polarity in a cell line: identification of an Aurora-A/PinsLINKER spindle orientation pathway

Asymmetric cell division is intensely studied because it can generate cellular diversity as well as maintain stem cell populations. Asymmetric cell division requires mitotic spindle alignment with intrinsic or extrinsic polarity cues, but mechanistic detail of this process is lacking. Here we develo...

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Bibliografiske detaljer
Main Authors: Johnston, Christopher A., Hirono, Keiko, Prehoda, Kenneth E., Doe, Chris Q.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789599/
https://ncbi.nlm.nih.gov/pubmed/19766567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.041
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