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Gαi generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts
Drosophila neuroblasts divide asymmetrically by aligning their mitotic spindle with cortical cell polarity to generate distinct sibling cell types. Neuroblasts asymmetrically localize Gαi, Pins, and Mud proteins; Pins/Gαi direct cortical polarity, whereas Mud is required for spindle orientation. It...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964812/ https://ncbi.nlm.nih.gov/pubmed/17726110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701812104 |
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