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Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)

Cystic fibrosis transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette (ABC) transporter superfamily, but little is known about how this ion channel that harbors an uninterrupted ion permeation pathway evolves from a transporter that works by alternately exposing its subs...

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Detalhes bibliográficos
Main Authors: Bai, Yonghong, Li, Min, Hwang, Tzyh-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206304/
https://ncbi.nlm.nih.gov/pubmed/22042986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110705
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