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Retinal Degeneration 3 (RD3) Protein Inhibits Catalytic Activity of Retinal Membrane Guanylyl Cyclase (RetGC) and Its Stimulation by Activating Proteins

Retinal membrane guanylyl cyclase (RetGC)(1) in the outer segments of vertebrate photoreceptors is controlled by guanylyl cyclase activating proteins (GCAPs), responding to light-dependent changes of the intracellular Ca(2+) concentrations. We present evidence that a different RetGC binding protein,...

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Bibliographic Details
Main Authors: Peshenko, Igor V., Olshevskaya, Elena V., Azadi, Seifollah, Molday, Laurie L., Molday, Robert S., Dizhoor, Alexander M.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206180/
https://ncbi.nlm.nih.gov/pubmed/21928830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201342b
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