Intracellular calcium overloading and oxidative stress in cardiomyocyte necrosis via a mitochondriocentric signal-transducer-effector pathway

Congestive heart failure (CHF), a common clinical syndrome, has reached epidemic proportions. Its disabling symptoms account for frequent hospitalizations and readmissions. Pathophysiological mechanisms that lead to CHF and account for its progressive nature are of considerable interest. Important s...

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Main Authors: Shaheen, Mazen, Cheema, Yaser, Shahbaz, Atta U, Bhattacharya, Syamal K, Weber, Karl T
Format: Artigo
Jezik:Inglês
Izdano: Pulsus Group Inc 2011
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206102/
https://ncbi.nlm.nih.gov/pubmed/22131852
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