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Cellular and molecular pathways to myocardial necrosis and replacement fibrosis

Fibrosis is a fundamental component of the adverse structural remodeling of myocardium present in the failing heart. Replacement fibrosis appears at sites of previous cardiomyocyte necrosis to preserve the structural integrity of the myocardium, but not without adverse functional consequences. The e...

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Detalhes bibliográficos
Main Authors: Gandhi, Malay S., Kamalov, German, Shahbaz, Atta U., Bhattacharya, Syamal K., Ahokas, Robert A., Sun, Yao, Gerling, Ivan C., Weber, Karl T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920342/
https://ncbi.nlm.nih.gov/pubmed/20405318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10741-010-9169-3
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