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Intracellular calcium overloading and oxidative stress in cardiomyocyte necrosis via a mitochondriocentric signal-transducer-effector pathway

Congestive heart failure (CHF), a common clinical syndrome, has reached epidemic proportions. Its disabling symptoms account for frequent hospitalizations and readmissions. Pathophysiological mechanisms that lead to CHF and account for its progressive nature are of considerable interest. Important s...

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Detalhes bibliográficos
Main Authors: Shaheen, Mazen, Cheema, Yaser, Shahbaz, Atta U, Bhattacharya, Syamal K, Weber, Karl T
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206102/
https://ncbi.nlm.nih.gov/pubmed/22131852
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