MITOCHONDRIOCENTRIC PATHWAY TO CARDIOMYOCYTE NECROSIS IN ALDOSTERONISM: CARDIOPROTECTIVE RESPONSES TO CARVEDILOL AND NEBIVOLOL

Foci of fibrosis, footprints of cardiomyocyte necrosis, are scattered throughout the failing myocardium and are a major component to its pathologic remodeling. Understanding pathogenic mechanisms contributing to hormone-mediated necrosis are therefore fundamental to developing cardioprotective strat...

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Autors principals: Cheema, Yaser, Sherrod, Jonathan N., Zhao, Wenyuan, Zhao, Tieqiang, Ahokas, Robert A., Sun, Yao, Gerling, Ivan C., Bhattacharya, Syamal K., Weber, Karl T.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135738/
https://ncbi.nlm.nih.gov/pubmed/21558884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31821cd83c
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