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Cation dyshomeostasis and cardiomyocyte necrosis: the Fleckenstein hypothesis revisited

An ongoing loss of cardiomyocytes to apoptotic and necrotic cell death pathways contributes to the progressive nature of heart failure. The pathophysiological origins of necrotic cell loss relate to the neurohormonal activation that accompanies acute and chronic stressor states and which includes ef...

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Detalhes bibliográficos
Main Authors: Borkowski, Brian J., Cheema, Yaser, Shahbaz, Atta U., Bhattacharya, Syamal K., Weber, Karl T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147115/
https://ncbi.nlm.nih.gov/pubmed/21398641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr063
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