Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia

BACKGROUND: Apolipoprotein E (apoE) is a major protein of the lipoprotein transport system that plays important roles in lipid homeostasis and protection from atherosclerosis. ApoE is characterized by structural plasticity and thermodynamic instability and can undergo significant structural rearrang...

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Bibliographic Details
Main Authors: Georgiadou, Dimitra, Chroni, Angeliki, Vezeridis, Alexander, Zannis, Vassilis I., Stratikos, Efstratios
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206067/
https://ncbi.nlm.nih.gov/pubmed/22069485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027037
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