Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia

BACKGROUND: Apolipoprotein E (apoE) is a major protein of the lipoprotein transport system that plays important roles in lipid homeostasis and protection from atherosclerosis. ApoE is characterized by structural plasticity and thermodynamic instability and can undergo significant structural rearrang...

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Main Authors: Georgiadou, Dimitra, Chroni, Angeliki, Vezeridis, Alexander, Zannis, Vassilis I., Stratikos, Efstratios
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206067/
https://ncbi.nlm.nih.gov/pubmed/22069485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027037
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