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Biophysical Analysis of Apolipoprotein E3 Variants Linked with Development of Type III Hyperlipoproteinemia

BACKGROUND: Apolipoprotein E (apoE) is a major protein of the lipoprotein transport system that plays important roles in lipid homeostasis and protection from atherosclerosis. ApoE is characterized by structural plasticity and thermodynamic instability and can undergo significant structural rearrang...

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Detalhes bibliográficos
Main Authors: Georgiadou, Dimitra, Chroni, Angeliki, Vezeridis, Alexander, Zannis, Vassilis I., Stratikos, Efstratios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206067/
https://ncbi.nlm.nih.gov/pubmed/22069485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027037
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