Kinetic Mechanistic and Structural Modeling Studies of Truncated Wild-Type LRRK2 and the Mutant G2019S

Lignende værker

• Type II Kinase Inhibitors Show an Unexpected Inhibition Mode against Parkinson’s Disease-Linked LRRK2 Mutant G2019S
  af: Liu, Min, et al.
  Udgivet: (2013)
• Spectroscopy and Kinetics of Wild-Type and Mutant Tyrosine Hydroxylase: Mechanistic Insight into O(2) Activation
  af: Chow, Marina S., et al.
  Udgivet: (2009)
• The Parkinson Disease-linked LRRK2 Protein Mutation I2020T Stabilizes an Active State Conformation Leading to Increased Kinase Activity
  af: Ray, Soumya, et al.
  Udgivet: (2014)
• Development of a Mechanism-based HTS Assay for Leucine Rich Repeat Kinase2—Discovery of LRRK2 Inhibitors
  af: Liu, Min, et al.
  Udgivet: (2010)
• Kinetic Mechanistic Studies of Cdk5/p25-Catalyzed H1P Phosphorylation: Metal Effect and Solvent Kinetic Isotope Effect
  af: Liu, Min, et al.
  Udgivet: (2010)