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MS3 eliminates ratio distortion in isobaric labeling-based multiplexed quantitative proteomics

Quantitative mass spectrometry-based proteomics is highly versatile, but not easily multiplexed. Isobaric labeling strategies allow mass spectrometry-based multiplexed proteome quantification; however, ratio distortion due to protein quantification interference is a common effect. We present a multi...

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Hlavní autoři: Ting, Lily, Rad, Ramin, Gygi, Steven P., Haas, Wilhelm
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205343/
https://ncbi.nlm.nih.gov/pubmed/21963607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1714
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