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Accurate Multiplexed Proteomics at the MS2 Level Using the Complement Reporter Ion Cluster
Isobaric labeling strategies, such as isobaric tags for relative and absolute quantitation (iTRAQ) or tandem mass tags (TMT), have promised to dramatically increase the power of quantitative proteomics. However, when applied to complex mixtures, both the accuracy and precision are undermined by inte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3771681/ https://ncbi.nlm.nih.gov/pubmed/23098179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac301962s |
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