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Isobaric labeling of intact gangliosides towards multiplexed LC-MS/MS based quantitative analysis

Gangliosides are sialic acid-containing glycosphingolipids recognized to play essential role in biological processes. Both the glycan and lipid structures influence their biological function, and thus necessitate their determination as intact molecular species. To our knowledge, no multiplexed metho...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Barrientos, Rodell C., Zhang, Qibin
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069520/
https://ncbi.nlm.nih.gov/pubmed/29384363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04044
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