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Isobaric labeling of intact gangliosides towards multiplexed LC-MS/MS based quantitative analysis

Gangliosides are sialic acid-containing glycosphingolipids recognized to play essential role in biological processes. Both the glycan and lipid structures influence their biological function, and thus necessitate their determination as intact molecular species. To our knowledge, no multiplexed metho...

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Publicado en:Anal Chem
Autores principales: Barrientos, Rodell C., Zhang, Qibin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069520/
https://ncbi.nlm.nih.gov/pubmed/29384363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04044
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