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Large-Scale and Deep Quantitative Proteome Profiling Using Isobaric Labeling Coupled with Two-Dimensional LC–MS/MS

Comprehensive, quantitative information on abundances of proteins and their posttranslational modifications (PTMs) can potentially provide novel biological insights into diseases pathogenesis and therapeutic intervention. Herein, we introduce a quantitative strategy utilizing isobaric stable isotope...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Gritsenko, Marina A., Xu, Zhe, Liu, Tao, Smith, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292933/
https://ncbi.nlm.nih.gov/pubmed/26867748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3524-6_14
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