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The Exquisite Regulation of PLD2 by a Wealth of Interacting Proteins: S6K, Grb2, Sos, WASp and Rac2 (and a Surprise Discovery: PLD2 Is a GEF)
PLD catalyzes the conversion of the membrane phospholipid phosphatidylcholine to choline and phosphatidic acid (PA). PLD's mission in the cell is two-fold: phospholipid turnover with maintenance of the structural integrity of cellular/intracellular membranes and cell signaling through PA and it...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204931/ https://ncbi.nlm.nih.gov/pubmed/21740967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.06.017 |
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