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THE MECHANISM OF CELL MEMBRANE RUFFLING RELIES ON A PHOSPHOLIPASE D2 (PLD2), GRB2 AND RAC2 ASSOCIATION

Membrane protrusion or ruffling is the formation of actin rich membrane protrusions, essential for cell motility. The exact mechanism of ruffling is not fully known. Using YFP and CFP fluorescent chimeras, we show for the first time a co-localization of Phospholipase D2 (PLD2) and Growth factor Rece...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mahankali, Madhu, Peng, Hong-Juan, Cox, Dianne, Gomez-Cambronero, Julian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095729/
https://ncbi.nlm.nih.gov/pubmed/21419846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.03.010
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