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A Novel Phospholipase D2-Grb2-WASp Heterotrimer Regulates Leukocyte Phagocytosis in a Two-Step Mechanism

Phagocytosis is a primary innate response of both macrophages and neutrophils involving the formation of filamentous actin (F-actin)-rich protrusions that are extended around opsonized pathogens to form a phagocytic cup, resulting in their subsequent internalization. The molecular mechanism for this...

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Autori principali: Kantonen, Samuel, Hatton, Nathaniel, Mahankali, Madhu, Henkels, Karen M., Park, Haein, Cox, Dianne, Gomez-Cambronero, Julian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209255/
https://ncbi.nlm.nih.gov/pubmed/21930784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05684-11
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