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Grb2 Is a Negative Modulator of the Intrinsic Ras-GEF Activity of hSos1
hSos1 is a Ras guanine-nucleotide exchange factor. It was suggested that the carboxyl-terminal region of hSos1 down-regulates hSos1 functionality and that the intrinsic guanine-nucleotide exchange activity of this protein may be different before and after stimulation of tyrosine kinase receptors. Us...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1525251/ https://ncbi.nlm.nih.gov/pubmed/16760435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-12-1104 |
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